We present a case report of a 66-year-old female who underwent salvage arthrodesis after a failed Scandinavian Total Ankle Replacement secondary to aseptic loosening and talar subsidence.Secondary to the loss of talar integrity the decision was made to proceed with revisional ankle arthrodesis.To maintain limb length the primary surgeon (EH) electe

Abstract Background Connecting the dots between the protein sequence and its function is of fundamental interest for protein engineers.In-silico methods are useful in this quest especially when structural information is not available.In this study we propose a mutant library screening tool called iSAR (innovative Sequence Activity Relationship) tha

The overall design ideas and system Power Control Cable integration ideas of local energy internet were introduced.In view of the system integration technology,the local energy internet was explored and studied from three aspects of planning and terminal access integration,equipment and system integration,integration between different systems.The a

Summary: Naive CD4+ Power Control Cable T cells are more resistant to age-related loss than naive CD8+ T cells, suggesting mechanisms that preferentially protect naive CD4+ T cells during aging.Here, we show that TRIB2 is more abundant in naive CD4+ than CD8+ T cells and counteracts quiescence exit by suppressing AKT activation.TRIB2 deficiency inc